Powder: -20°C for 3 years | In solvent: -80°C for 1 year
eIF4A i28, an inhibitor of the eukaryotic initiation factor-4A (eIF4A) with an IC50 of 8.60 μM in an eIF4A ATPase assay, effectively reduces the viability of BJAB Burkitt lymphoma cells, as indicated by an EC50 of 0.46 μM in a CellTiter-Glo (CTG) luminescence cell viability assay. This compound functions as an RNA-competitive, ATP-uncompetitive eIF4A inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | 35 days | $ 498.00 |
Description | eIF4A i28, an inhibitor of the eukaryotic initiation factor-4A (eIF4A) with an IC50 of 8.60 μM in an eIF4A ATPase assay, effectively reduces the viability of BJAB Burkitt lymphoma cells, as indicated by an EC50 of 0.46 μM in a CellTiter-Glo (CTG) luminescence cell viability assay. This compound functions as an RNA-competitive, ATP-uncompetitive eIF4A inhibitor. |
Molecular Weight | 416.43 |
Formula | C24H20N2O5 |
CAS No. | 2861994-92-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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eIF4A i28 2861994-92-3 inhibitor inhibit