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N-hexanoyl-L-Homoserine lactone

🥰Excellent
Catalog No. T22375Cas No. 147852-83-3
Alias C6-HSL

N-hexanoyl-L-Homoserine lactone (C6-HSL), a small diffusible signaling molecule, is involved in controlling gene expression, affecting cellular metabolism, and quorum sensing.

N-hexanoyl-L-Homoserine lactone

N-hexanoyl-L-Homoserine lactone

🥰Excellent
Purity: 99.96%
Catalog No. T22375Alias C6-HSLCas No. 147852-83-3
N-hexanoyl-L-Homoserine lactone (C6-HSL), a small diffusible signaling molecule, is involved in controlling gene expression, affecting cellular metabolism, and quorum sensing.
Pack SizePriceAvailabilityQuantity
5 mg$31In Stock
10 mg$56In Stock
25 mg$106In Stock
50 mg$172In Stock
100 mg$278In Stock
200 mg$417In Stock
500 mg$678In Stock
1 mL x 10 mM (in DMSO)$35In Stock
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Purity:99.96%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
N-hexanoyl-L-Homoserine lactone (C6-HSL), a small diffusible signaling molecule, is involved in controlling gene expression, affecting cellular metabolism, and quorum sensing.
SynonymsC6-HSL
Chemical Properties
Molecular Weight199.25
FormulaC10H17NO3
Cas No.147852-83-3
SmilesCCCCCC(=O)N[C@H]1CCOC1=O
Relative Density.1.08 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from moisture,keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 30 mg/mL (150.56 mM), Sonication is recommended.
PBS (pH 7.2): 10 mg/mL (50.19 mM), Sonication is recommended.
DMF: 30 mg/mL (150.56 mM), Sonication is recommended.
Ethanol: 30 mg/mL (150.56 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (10.04 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
PBS (pH 7.2)/DMSO/DMF/Ethanol
1mg5mg10mg50mg
1 mM5.0188 mL25.0941 mL50.1882 mL250.9410 mL
5 mM1.0038 mL5.0188 mL10.0376 mL50.1882 mL
10 mM0.5019 mL2.5094 mL5.0188 mL25.0941 mL
20 mM0.2509 mL1.2547 mL2.5094 mL12.5471 mL
50 mM0.1004 mL0.5019 mL1.0038 mL5.0188 mL
DMSO/DMF/Ethanol
1mg5mg10mg50mg
100 mM0.0502 mL0.2509 mL0.5019 mL2.5094 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

N-hexanoyl-L-Homoserine lactoneNhexanoylLHomoserine lactoneN hexanoyl L Homoserine lactoneInhibitorinhibitBacterial
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