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JX237

Name: JX237
Brand: TargetMol
SKU: T89913
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T89913Cas No. 1021125-90-5

Alias JX 237

JX237 is a potent inhibitor of the epithelial neutral amino acid transporter protein B0AT1 (SLC6A19), a transporter protein for the uptake of neutralizing amino acids by the liver, and can be used in the study of cardiovascular disease.

JX237

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Purity: 99.19%

Catalog No. T89913Alias JX 237Cas No. 1021125-90-5

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$32	In Stock	In Stock
5 mg	$73	In Stock	In Stock
10 mg	$129	In Stock	In Stock
25 mg	$263	In Stock	In Stock
50 mg	$428	In Stock	In Stock
100 mg	$689	-	In Stock
200 mg	$973	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.19%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	JX237 is a potent inhibitor of the epithelial neutral amino acid transporter protein B0AT1 (SLC6A19), a transporter protein for the uptake of neutralizing amino acids by the liver, and can be used in the study of cardiovascular disease.
Synonyms	JX 237

Chemical Properties

Molecular Weight	271.15
Formula	C₁₁H₁₅BrN₂O
Cas No.	1021125-90-5
Smiles	O=C(NCC)CNC1=CC=C(Br)C(=C1)C
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200 mg/mL (737.6 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6880 mL	18.4400 mL	36.8800 mL	184.3998 mL
5 mM	0.7376 mL	3.6880 mL	7.3760 mL	36.8800 mL
10 mM	0.3688 mL	1.8440 mL	3.6880 mL	18.4400 mL
20 mM	0.1844 mL	0.9220 mL	1.8440 mL	9.2200 mL
50 mM	0.0738 mL	0.3688 mL	0.7376 mL	3.6880 mL
100 mM	0.0369 mL	0.1844 mL	0.3688 mL	1.8440 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc