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JX237

Name: JX237
Brand: TargetMol
SKU: T89913
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T89913Cas No. 1021125-90-5

Alias JX 237

JX237 is a potent inhibitor of the epithelial neutral amino acid transporter protein B0AT1 (SLC6A19), a transporter protein for the uptake of neutralizing amino acids by the liver, and can be used in the study of cardiovascular disease.

JX237

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Purity: 99.19%

Catalog No. T89913Alias JX 237Cas No. 1021125-90-5

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$32	In Stock	In Stock
5 mg	$73	In Stock	In Stock
10 mg	$129	In Stock	In Stock
25 mg	$263	In Stock	In Stock
50 mg	$428	In Stock	In Stock
100 mg	$689	-	In Stock
200 mg	$973	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.19%

Appearance:Solid

Color:Yellow

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	JX237 is a potent inhibitor of the epithelial neutral amino acid transporter protein B0AT1 (SLC6A19), a transporter protein for the uptake of neutralizing amino acids by the liver, and can be used in the study of cardiovascular disease.
Synonyms	JX 237

Chemical Properties

Molecular Weight	271.15
Formula	C₁₁H₁₅BrN₂O
Cas No.	1021125-90-5
Smiles	O=C(NCC)CNC1=CC=C(Br)C(=C1)C

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200 mg/mL (737.6 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6880 mL	18.4400 mL	36.8800 mL	184.3998 mL
5 mM	0.7376 mL	3.6880 mL	7.3760 mL	36.8800 mL
10 mM	0.3688 mL	1.8440 mL	3.6880 mL	18.4400 mL
20 mM	0.1844 mL	0.9220 mL	1.8440 mL	9.2200 mL
50 mM	0.0738 mL	0.3688 mL	0.7376 mL	3.6880 mL
100 mM	0.0369 mL	0.1844 mL	0.3688 mL	1.8440 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc