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BN82002 hydrochloride

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Catalog No. T38447Cas No. 1049740-43-3
Alias BN 82002 hydrochloride

BN82002 hydrochloride is a CDC25 phosphatase inhibitor that inhibits the phosphatase activity of recombinant human CDC25A, B, and C in vitro, arresting the cell cycle and reducing tumour growth in mice.

BN82002 hydrochloride

BN82002 hydrochloride

🥰Excellent
Catalog No. T38447Alias BN 82002 hydrochlorideCas No. 1049740-43-3
BN82002 hydrochloride is a CDC25 phosphatase inhibitor that inhibits the phosphatase activity of recombinant human CDC25A, B, and C in vitro, arresting the cell cycle and reducing tumour growth in mice.
Pack SizePriceAvailabilityQuantity
2 mg$278In Stock
5 mg$418In Stock
1 mL x 10 mM (in DMSO)$528In Stock
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Product Introduction

Bioactivity
Description
BN82002 hydrochloride is a CDC25 phosphatase inhibitor that inhibits the phosphatase activity of recombinant human CDC25A, B, and C in vitro, arresting the cell cycle and reducing tumour growth in mice.
Targets&IC50
CDC25C:5.4 μM, CDC25A:2.4 μM, CDC25B3:6.3 μM, CDC25C-cat:4.6 μM, CDC25B2:3.9 μM
In vitro
Methods: RAW264.7 cells were treated with BN82002 hydrochloride (0-100 μM, 24 hours), and cell viability was measured by MTT assay.
Results: BN82002 hydrochloride reduced cell viability by 20% at a concentration of 100 μM. [2]
AliasBN 82002 hydrochloride
Chemical Properties
Molecular Weight395.88
FormulaC19H26ClN3O4
Cas No.1049740-43-3
SmilesCl.O=N(=O)C1=CC=C(C=C1)CCN(C)CC2=CC(=CC(OC)=C2O)N(C)C
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from moisture,keep away from direct sunlight | store at 4°C | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 200 mg/mL (505.2 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5260 mL12.6301 mL25.2602 mL126.3009 mL
5 mM0.5052 mL2.5260 mL5.0520 mL25.2602 mL
10 mM0.2526 mL1.2630 mL2.5260 mL12.6301 mL
20 mM0.1263 mL0.6315 mL1.2630 mL6.3150 mL
50 mM0.0505 mL0.2526 mL0.5052 mL2.5260 mL
100 mM0.0253 mL0.1263 mL0.2526 mL1.2630 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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