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BN82002 hydrochloride is a CDC25 phosphatase inhibitor that inhibits the phosphatase activity of recombinant human CDC25A, B, and C in vitro, arresting the cell cycle and reducing tumour growth in mice.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $278 | In Stock | |
5 mg | $418 | In Stock | |
1 mL x 10 mM (in DMSO) | $528 | In Stock |
Description | BN82002 hydrochloride is a CDC25 phosphatase inhibitor that inhibits the phosphatase activity of recombinant human CDC25A, B, and C in vitro, arresting the cell cycle and reducing tumour growth in mice. |
Targets&IC50 | CDC25C:5.4 μM, CDC25A:2.4 μM, CDC25B3:6.3 μM, CDC25C-cat:4.6 μM, CDC25B2:3.9 μM |
In vitro | Methods: RAW264.7 cells were treated with BN82002 hydrochloride (0-100 μM, 24 hours), and cell viability was measured by MTT assay. Results: BN82002 hydrochloride reduced cell viability by 20% at a concentration of 100 μM. [2] |
Alias | BN 82002 hydrochloride |
Molecular Weight | 395.88 |
Formula | C19H26ClN3O4 |
Cas No. | 1049740-43-3 |
Smiles | Cl.O=N(=O)C1=CC=C(C=C1)CCN(C)CC2=CC(=CC(OC)=C2O)N(C)C |
Relative Density. | no data available |
Storage | keep away from moisture,keep away from direct sunlight | store at 4°C | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 200 mg/mL (505.2 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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