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Sulfamoxole

Name: Sulfamoxole
Brand: TargetMol
SKU: T21435
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T21435Cas No. 729-99-7

Alias Sulfamoxol, Oxazole, Oxasulfa, NSC-683535, NSC683535, NSC 683535

Sulfamoxole (Sulfamoxol) is an antibacterial belonging to sulfonamide.

Sulfamoxole

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Purity: 99.41%

Catalog No. T21435Alias Sulfamoxol, Oxazole, Oxasulfa, NSC-683535, NSC683535, NSC 683535Cas No. 729-99-7

Sulfamoxole (Sulfamoxol) is an antibacterial belonging to sulfonamide.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$31	In Stock	In Stock
10 mg	$45	In Stock	In Stock
25 mg	$73	In Stock	In Stock
50 mg	$106	In Stock	In Stock
100 mg	$157	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.41%

Appearance:Solid

Color:White to Yellow

Resource Download

COA HNMR HPLC

Product Introduction

Sulfamoxole AI Summary

Sulfamoxole displays moderate liver toxicity, evidenced by elevated serum enzyme activity levels, indicating cytolytic, cholestatic, and mixed liver toxicity in clinical studies. However, it is not associated with severe hepatitis, chronic liver disease, cirrhosis, granulomatous liver disease, vascular-related liver damage, steatosis, or liver tumors. The compound exhibits antiviral properties, including inhibition of SARS-CoV-2 induced cytotoxicity in both Caco-2 and VERO-6 cells at a 10 µM concentration with varying inhibition rates. It also shows activity against SARS-CoV-2 3CL-Pro protease, albeit with a negative inhibition percentage at 20 µM. Furthermore, Sulfamoxole has inhibitory activity against the human HDAC6 enzyme, achieving inhibition rates of 12.13% and 32.62% using different peptide substrates..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Sulfamoxole (Sulfamoxol) is an antibacterial belonging to sulfonamide.
Synonyms	Sulfamoxol, Oxazole, Oxasulfa, NSC-683535, NSC683535, NSC 683535

Chemical Properties

Molecular Weight	267.3
Formula	C₁₁H₁₃N₃O₃S
Cas No.	729-99-7
Smiles	CC1=C(C)N=C(NS(=O)(=O)C2=CC=C(N)C=C2)O1
Relative Density.	1.411g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: Insoluble

DMSO: 65 mg/mL (243.17 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7411 mL	18.7056 mL	37.4111 mL	187.0557 mL
5 mM	0.7482 mL	3.7411 mL	7.4822 mL	37.4111 mL
10 mM	0.3741 mL	1.8706 mL	3.7411 mL	18.7056 mL
20 mM	0.1871 mL	0.9353 mL	1.8706 mL	9.3528 mL
50 mM	0.0748 mL	0.3741 mL	0.7482 mL	3.7411 mL
100 mM	0.0374 mL	0.1871 mL	0.3741 mL	1.8706 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc