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CID-1067700

Name: CID-1067700
Brand: TargetMol
SKU: T7558
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7558Cas No. 314042-01-8

CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 with a Ki of 13 nM).

CID-1067700

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Purity: 99.46%

Catalog No. T7558Cas No. 314042-01-8

CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 with a Ki of 13 nM).

Pack Size	Price	Availability
1 mg	$30	In Stock
2 mg	$44	In Stock
5 mg	$68	In Stock
10 mg	$113	In Stock
25 mg	$198	In Stock
50 mg	$259	In Stock
100 mg	$336	In Stock
1 mL x 10 mM (in DMSO)	$75	In Stock

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Batch Information

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Purity:99.46%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 with a Ki of 13 nM).
Targets&IC50	Rab7:13 nM
In vitro	CID-1067700 binds the nucleotide binding pocket of Rab7 with a Ki value of 13 nM, preventing BODIPY-linked GTP and GDP binding with EC50 values of 11.2 and 21 nM, respectively[1].

Chemical Properties

Molecular Weight	390.48
Formula	C₁₈H₁₈N₂O₄S₂
Cas No.	314042-01-8
Smiles	CC1(C)Cc2c(CO1)sc(NC(=S)NC(=O)c1ccccc1)c2C(O)=O
Relative Density.	1.410 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 68 mg/mL (174 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5610 mL	12.8048 mL	25.6095 mL	128.0475 mL
5 mM	0.5122 mL	2.5610 mL	5.1219 mL	25.6095 mL
10 mM	0.2561 mL	1.2805 mL	2.5610 mL	12.8048 mL
20 mM	0.1280 mL	0.6402 mL	1.2805 mL	6.4024 mL
50 mM	0.0512 mL	0.2561 mL	0.5122 mL	2.5610 mL
100 mM	0.0256 mL	0.1280 mL	0.2561 mL	1.2805 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc