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Valacyclovir hydrochloride

Name: Valacyclovir hydrochloride
Brand: TargetMol
SKU: T1087
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1087Cas No. 124832-27-5

Alias Valaciclovir hydrochloride, Valaciclovir HCl

Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an acyclovir prodrug that, upon metabolism, inhibits viral DNA replication.

Valacyclovir hydrochloride

🥰Excellent

Purity: 99.88%

Catalog No. T1087Alias Valaciclovir hydrochloride, Valaciclovir HClCas No. 124832-27-5

Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an acyclovir prodrug that, upon metabolism, inhibits viral DNA replication.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$32	In Stock	In Stock
50 mg	$56	In Stock	In Stock
100 mg	$98	In Stock	In Stock
500 mg	$197	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$35	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.88%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an acyclovir prodrug that, upon metabolism, inhibits viral DNA replication.
Targets&IC50	HSV1:2.9 μg/mL (IC50)
In vitro	In male CD rats, Valaciclovir was absorbed orally, efficiently metabolized and rapidly distributed.
In vivo	Valaciclovir is the L-valine ester of aciclovir, the absorption of which occurs in the intestinal lumen and is converted to the L-valine ester of aciclovir.Valaciclovir inhibits the uptake of dipeptide transporter protein substrates, e.g., cephalosporin.
Synonyms	Valaciclovir hydrochloride, Valaciclovir HCl

Chemical Properties

Molecular Weight	360.80
Formula	C₁₃H₂₀N₆O₄·HCl
Cas No.	124832-27-5
Smiles	Cl.CC(C)[C@H](N)C(=O)OCCOCn1cnc2c1nc(N)[nH]c2=O
Relative Density.	1.55g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55.00 mg/mL (152.44 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.54 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7716 mL	13.8581 mL	27.7162 mL	138.5809 mL
5 mM	0.5543 mL	2.7716 mL	5.5432 mL	27.7162 mL
10 mM	0.2772 mL	1.3858 mL	2.7716 mL	13.8581 mL
20 mM	0.1386 mL	0.6929 mL	1.3858 mL	6.9290 mL
50 mM	0.0554 mL	0.2772 mL	0.5543 mL	2.7716 mL
100 mM	0.0277 mL	0.1386 mL	0.2772 mL	1.3858 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc