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Tetracaine hydrochloride

Name: Tetracaine hydrochloride
Brand: TargetMol
SKU: T1198
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1198Cas No. 136-47-0

Alias Tetracaine HCl, Amethocalne HCl, Amethocaine hydrochloride

Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been used for surface and spinal anesthesia.

Tetracaine hydrochloride

🥰Excellent

Purity: 99.94%

Catalog No. T1198Alias Tetracaine HCl, Amethocalne HCl, Amethocaine hydrochlorideCas No. 136-47-0

Pack Size	Price	Availability	Quantity
200 mg	$29	In Stock

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Purity:99.94%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been used for surface and spinal anesthesia.
Synonyms	Tetracaine HCl, Amethocalne HCl, Amethocaine hydrochloride

Chemical Properties

Molecular Weight	300.82
Formula	C₁₅H₂₅ClN₂O₂
Cas No.	136-47-0
Smiles	Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C
Relative Density.	1.1279 g/cm3 (Estimated)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 28.00 mg/mL (93.08 mM), Sonication is recommended.

H2O: 55.00 mg/mL (182.83 mM), Sonication is recommended.

DMSO: 40.00 mg/mL (132.97 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	3.3242 mL	16.6212 mL	33.2425 mL	166.2124 mL
5 mM	0.6648 mL	3.3242 mL	6.6485 mL	33.2425 mL
10 mM	0.3324 mL	1.6621 mL	3.3242 mL	16.6212 mL
20 mM	0.1662 mL	0.8311 mL	1.6621 mL	8.3106 mL
50 mM	0.0665 mL	0.3324 mL	0.6648 mL	3.3242 mL

DMSO/H2O

	1mg	5mg	10mg	50mg
100 mM	0.0332 mL	0.1662 mL	0.3324 mL	1.6621 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc