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Glucosamine hydrochloride

Name: Glucosamine hydrochloride
Brand: TargetMol
SKU: T2941
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2941Cas No. 66-84-2

Alias D-(+)-Glucosamine hydrochloride, Chitosamine hydrochloride, Chitosamine HCl, 2-Amino-2-deoxy-glucose HCl

Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.

Glucosamine hydrochloride

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Purity: 99.77%

Catalog No. T2941Alias D-(+)-Glucosamine hydrochloride, Chitosamine hydrochloride, Chitosamine HCl, 2-Amino-2-deoxy-glucose HClCas No. 66-84-2

Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	In Stock	In Stock
5 g	$39	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.77%

Appearance:Solid

Color:White

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COA LCMS HPLC HNMR

Product Introduction

Glucosamine hydrochloride AI Summary

Glucosamine hydrochloride is a multifunctional inhibitor with significant bioactivity across various assays. It is a confirmed inhibitor of BAZ2B with a potency of 1258.9 nM and shows inhibitory activity against Human Apurinic/apyrimidinic Endonuclease 1 (APE1) with a potency of 2818.4 nM. Additionally, it acts as an inhibitor in a primary qHTS assay for delayed death inhibitors of the malarial parasite plastid with a potency of 13115.4 nM and demonstrates activity in a cell-based assay targeting B-Galactocerebrosidase with a potency of 707.9 nM. Moreover, Glucosamine hydrochloride inhibits sodium fluorescein uptake by 60.72% in OATP1B1-transfected CHO cells and by 87.62% in OATP1B3-transfected CHO cells at a concentration of 10 μM. The compound also exhibits anti-inflammatory properties, significantly reducing xylene-induced ear edema in ICR mice by 64.3% at a dose of 10 μmol/kg when administered orally..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.
Synonyms	D-(+)-Glucosamine hydrochloride, Chitosamine hydrochloride, Chitosamine HCl, 2-Amino-2-deoxy-glucose HCl

Chemical Properties

Molecular Weight	215.63
Formula	C₆H₁₃NO₅·HCl
Cas No.	66-84-2
Smiles	Cl.O[C@H]1[C@H](O)[C@@H](CO)OC(O)[C@@H]1N
Relative Density.	no data available

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 34 mg/mL (157.68 mM), Sonication is recommended.

DMSO: 55 mg/mL (255.07 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (9.28 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.6376 mL	23.1879 mL	46.3757 mL	231.8787 mL
5 mM	0.9275 mL	4.6376 mL	9.2751 mL	46.3757 mL
10 mM	0.4638 mL	2.3188 mL	4.6376 mL	23.1879 mL
20 mM	0.2319 mL	1.1594 mL	2.3188 mL	11.5939 mL
50 mM	0.0928 mL	0.4638 mL	0.9275 mL	4.6376 mL
100 mM	0.0464 mL	0.2319 mL	0.4638 mL	2.3188 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc