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OU749

Name: OU749
Brand: TargetMol
SKU: T22128
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T22128Cas No. 519170-13-9

OU749 is a γ-glutamyl transferase (GGT) inhibitor with an intrinsic Ki of 17.6 μM.

OU749

🥰Excellent

Purity: 99.50%

Catalog No. T22128Cas No. 519170-13-9

OU749 is a γ-glutamyl transferase (GGT) inhibitor with an intrinsic Ki of 17.6 μM.

Pack Size	Price	Availability
2 mg	$42	In Stock
5 mg	$81	In Stock
10 mg	$129	In Stock
25 mg	$219	In Stock
50 mg	$326	In Stock
100 mg	$485	In Stock
500 mg	$1,060	In Stock
1 mL x 10 mM (in DMSO)	$64	In Stock

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Batch Information

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Purity:99.50%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	OU749 is a γ-glutamyl transferase (GGT) inhibitor with an intrinsic Ki of 17.6 μM.
Targets&IC50	GGTase I:17.6 μM(Ki)

Chemical Properties

Molecular Weight	361.44
Formula	C₁₆H₁₅N₃O₃S₂
Cas No.	519170-13-9
Smiles	COC1=CC=C(CC2=NN=C(NS(=O)(=O)C3=CC=CC=C3)S2)C=C1
Relative Density.	1.31g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (138.34 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7667 mL	13.8336 mL	27.6671 mL	138.3355 mL
5 mM	0.5533 mL	2.7667 mL	5.5334 mL	27.6671 mL
10 mM	0.2767 mL	1.3834 mL	2.7667 mL	13.8336 mL
20 mM	0.1383 mL	0.6917 mL	1.3834 mL	6.9168 mL
50 mM	0.0553 mL	0.2767 mL	0.5533 mL	2.7667 mL
100 mM	0.0277 mL	0.1383 mL	0.2767 mL	1.3834 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc