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KK181N1

(Synonyms: KK-181N1, KK 181N1) Copy Product Info
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Synonyms: KK-181N1, KK 181N1

Catalog No. T204264 Copy Product Info
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KK181N1 is a triazolide selective inhibitor of the karrikin (KAR) receptor KAI2 that binds non-covalently to the catalytic pocket of KAI2 and has no significant effect on the related receptor AtD14. KK181N1 selectively inhibits KAR-induced phenotypes in Arabidopsis.
KK181N1
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$59-In Stock
5 mg$143-In Stock
10 mg$228-In Stock
25 mg$463-In Stock
50 mg$738-In Stock
100 mg$1,180-In Stock
1 mL x 10 mM (in DMSO)$157-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
KK181N1 is a triazolide selective inhibitor of the karrikin (KAR) receptor KAI2 that binds non-covalently to the catalytic pocket of KAI2 and has no significant effect on the related receptor AtD14. KK181N1 selectively inhibits KAR-induced phenotypes in Arabidopsis.
SynonymsKK-181N1, KK 181N1
Chemical Properties
Molecular Weight228.25
FormulaC12H12N4O
SmilesCC1=C2C(CCN2C(N3N=NC=C3)=O)=CC=C1
Storage & Solubility Information
StorageKeep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 40 mg/mL (175.25 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.3812 mL21.9058 mL43.8116 mL219.0581 mL
5 mM0.8762 mL4.3812 mL8.7623 mL43.8116 mL
10 mM0.4381 mL2.1906 mL4.3812 mL21.9058 mL
20 mM0.2191 mL1.0953 mL2.1906 mL10.9529 mL
50 mM0.0876 mL0.4381 mL0.8762 mL4.3812 mL
100 mM0.0438 mL0.2191 mL0.4381 mL2.1906 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion
Related Tags: KK181N1 chemical structure | KK181N1 formula | KK181N1 molecular weight