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2-Methoxyestrone

Name: 2-Methoxyestrone
Brand: TargetMol
SKU: T13481
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T13481Cas No. 362-08-3

2-Methoxyestrone is a methoxylated catechol estrogen and the principal metabolite of 2-hydroxyestrone [a nonuterotropic metabolite of estradiol].

2-Methoxyestrone

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Purity: 99.18%

Catalog No. T13481Cas No. 362-08-3

2-Methoxyestrone is a methoxylated catechol estrogen and the principal metabolite of 2-hydroxyestrone [a nonuterotropic metabolite of estradiol].

Pack Size	Price	Availability
1 mg	$42	In Stock
5 mg	$98	In Stock
10 mg	$163	In Stock
25 mg	$297	In Stock
50 mg	$439	In Stock
100 mg	$648	In Stock
200 mg	$926	In Stock
1 mL x 10 mM (in DMSO)	$108	In Stock

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Batch Information

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Purity:99.18%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	2-Methoxyestrone is a methoxylated catechol estrogen and the principal metabolite of 2-hydroxyestrone [a nonuterotropic metabolite of estradiol].
In vivo	2-Methoxyestrone, given at noon of proestrus, significantly augments the magnitude of the preovulatory prolactin rise possibly by inhibiting the formation of endogenous 2-hydroxyestrogens in the brain[2].

Chemical Properties

Molecular Weight	300.39
Formula	C₁₉H₂₄O₃
Cas No.	362-08-3
Smiles	[H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])c3cc(OC)c(O)cc3CC[C@@]21[H]
Relative Density.	1.172g/cm3

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 44 mg/mL (146.48 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3290 mL	16.6450 mL	33.2901 mL	166.4503 mL
5 mM	0.6658 mL	3.3290 mL	6.6580 mL	33.2901 mL
10 mM	0.3329 mL	1.6645 mL	3.3290 mL	16.6450 mL
20 mM	0.1665 mL	0.8323 mL	1.6645 mL	8.3225 mL
50 mM	0.0666 mL	0.3329 mL	0.6658 mL	3.3290 mL
100 mM	0.0333 mL	0.1665 mL	0.3329 mL	1.6645 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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