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Fervenulin

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Catalog No. T15277Cas No. 483-57-8

Fervenulin is isolated from a nematicidal actinomycete Streptomyces sp. CMU-MH021 has nematicidal activity. CMU-MH021 inhibits egg hatch(MICs: 30 μg/mL) and J2 mortality(MICs: 120 μg/mL) of M. incognita.

Fervenulin

Fervenulin

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Purity: 99.75%
Catalog No. T15277Cas No. 483-57-8
Fervenulin is isolated from a nematicidal actinomycete Streptomyces sp. CMU-MH021 has nematicidal activity. CMU-MH021 inhibits egg hatch(MICs: 30 μg/mL) and J2 mortality(MICs: 120 μg/mL) of M. incognita.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$68In StockIn Stock
5 mg$146In StockIn Stock
10 mg$233In StockIn Stock
25 mg$397In StockIn Stock
50 mg$556In StockIn Stock
100 mg$738In StockIn Stock
200 mg$993-In Stock
1 mL x 10 mM (in DMSO)$119In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.75%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
Fervenulin is isolated from a nematicidal actinomycete Streptomyces sp. CMU-MH021 has nematicidal activity. CMU-MH021 inhibits egg hatch(MICs: 30 μg/mL) and J2 mortality(MICs: 120 μg/mL) of M. incognita.
Targets&IC50
M. incognita:120 μg/mL (MIC, J2 mortality), M. incognita:30 μg/mL(MIC, egg hatch)
In vitro
Fervenulin shows a killing effect on second-stage nematode juveniles of M. incognita up to 100% after incubation for 96 h at the concentration of 250 μg/mL. Fervenulin displays a broad range of biological activities, e.g., in vitro antibacterial, antiparasitic, antifungal, and antitumor properties.
Chemical Properties
Molecular Weight193.16
FormulaC7H7N5O2
Cas No.483-57-8
SmilesCn1c2nncnc2c(=O)n(C)c1=O
Relative Density.1.4225 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (284.74 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.1771 mL25.8853 mL51.7706 mL258.8528 mL
5 mM1.0354 mL5.1771 mL10.3541 mL51.7706 mL
10 mM0.5177 mL2.5885 mL5.1771 mL25.8853 mL
20 mM0.2589 mL1.2943 mL2.5885 mL12.9426 mL
50 mM0.1035 mL0.5177 mL1.0354 mL5.1771 mL
100 mM0.0518 mL0.2589 mL0.5177 mL2.5885 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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