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Glutamyl-glutamic acid

Name: Glutamyl-glutamic acid
Brand: TargetMol
SKU: T20362
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20362Cas No. 3929-61-1

Alias N-L-alpha-Glutamyl-L-glutamic acid, Glu-glu, Dipotassium glutamyl-glutamate

Glutamyl-glutamic acid (Glu-glu) is an Interpeptide Bridge in the Murein of Some Micrococci and Arthrobacter sp..

Glutamyl-glutamic acid

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🥰Excellent

Catalog No. T20362Alias N-L-alpha-Glutamyl-L-glutamic acid, Glu-glu, Dipotassium glutamyl-glutamateCas No. 3929-61-1

Glutamyl-glutamic acid (Glu-glu) is an Interpeptide Bridge in the Murein of Some Micrococci and Arthrobacter sp..

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$31	In Stock	In Stock
100 mg	$48	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:≥98%

Resource Download

COA HNMR

Product Introduction

Glutamyl-glutamic acid AI Summary

Glutamyl-glutamic acid shows inhibitory activity against expressed rat Glutamate carboxypeptidase II, with an IC50 value of 750.0 nM at a substrate concentration of 5 µM. It also exhibits bioactivity with human PEPT1, having an EC50 of 1,000,000.0 nM for activation and reaching a maximum activation of 111.0% relative to Gly-Sar. Furthermore, Glutamyl-glutamic acid has an IC50 of 620,000.0 nM for binding affinity as an inhibitor of [14C]Gly-Sar uptake in MDCK cells. The ratio of %GSmax to EC50 for human PEPT1 activation is 110.0, suggesting potential bioactivity. Additionally, the compound inhibits nitrogen-starved wild type sigma1278b yeast Gap1-mediated amino acid uptake at 5 mM after 60 seconds with less than 15.0% inhibition relative to L-citrulline..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Glutamyl-glutamic acid (Glu-glu) is an Interpeptide Bridge in the Murein of Some Micrococci and Arthrobacter sp..
Synonyms	N-L-alpha-Glutamyl-L-glutamic acid, Glu-glu, Dipotassium glutamyl-glutamate

Chemical Properties

Molecular Weight	276.24
Formula	C₁₀H₁₆N₂O₇
Cas No.	3929-61-1
Smiles	N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Relative Density.	1.47 g/cm3
Sequence	Glu-Glu
Sequence Short	EE

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (199.1 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6200 mL	18.1002 mL	36.2004 mL	181.0020 mL
5 mM	0.7240 mL	3.6200 mL	7.2401 mL	36.2004 mL
10 mM	0.3620 mL	1.8100 mL	3.6200 mL	18.1002 mL
20 mM	0.1810 mL	0.9050 mL	1.8100 mL	9.0501 mL
50 mM	0.0724 mL	0.3620 mL	0.7240 mL	3.6200 mL
100 mM	0.0362 mL	0.1810 mL	0.3620 mL	1.8100 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc