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Fosfomycin calcium

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Catalog No. T3131Cas No. 26016-98-8
Alias Phosphomycin calcium salt, Fosmicin

Fosfomycin calcium (Phosphomycin calcium salt) is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis.

Fosfomycin calcium

Fosfomycin calcium

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Catalog No. T3131Alias Phosphomycin calcium salt, FosmicinCas No. 26016-98-8
Fosfomycin calcium (Phosphomycin calcium salt) is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mg$33In StockIn Stock
500 mg$74-In Stock
1 g$108-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Solid
Color:White
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Product Introduction

Fosfomycin calcium AI Summary
Fosfomycin calcium shows bioactivities as an inhibitor in various assays. It acts as an inhibitor of Influenza NS1 Protein Function and AmpC Beta-Lactamase, both with a potency of 316.2 nM. Additionally, it inhibits Chronic Active B-Cell Receptor Signaling with a potency of 29092.9 nM and Human Apurinic/apyrimidinic Endonuclease 1 (APE1) with a potency of 50118.7 nM..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Fosfomycin calcium (Phosphomycin calcium salt) is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis.
SynonymsPhosphomycin calcium salt, Fosmicin
Chemical Properties
Molecular Weight176.12
FormulaC3H5CaO4P
Cas No.26016-98-8
SmilesC[C@H]1O[C@H]1P([O-])([O-])=O.[Ca+2]
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: Slightly soluble

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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