Shopping Cart

Your shopping cart is currently empty

β-Alanine

Name: β-Alanine
Brand: TargetMol
SKU: T0627
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T0627Cas No. 107-95-9

Alias beta-Alanine, 3-Aminopropanoic acid, 2-Carboxyethylamine

β-Alanine (3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotransmitter by activating glycine and GABA receptors.

β-Alanine

Copy Product Info

😃Good

Purity: 99.80%

Catalog No. T0627Alias beta-Alanine, 3-Aminopropanoic acid, 2-CarboxyethylamineCas No. 107-95-9

Pack Size	Price	USA Warehouse	Global Warehouse
500 mg	$40	In Stock	In Stock
1 g	$56	In Stock	In Stock
2 g	$80	-	In Stock
5 g	$123	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.80%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

β-Alanine AI Summary

β-Alanine exhibits multifaceted bioactivity across various biochemical and pharmacological pathways. It enhances cleavage rates of hairpin ribozymes at concentrations of 2 mM and 5 mM in the presence of 0.5 uM magnesium ions, with kinetic rate constants (K obs) of 0.018 and 0.03, respectively. The compound also displays inhibitory properties, such as reducing fluorescence intensity of copper-free calcein in bovine serum albumin by 50% at 20% concentration, and inhibiting N-methyl-D-aspartate glutamate receptor 1 with an IC50 value of 11,600 nM. β-Alanine significantly inhibits CD40 expression in BCL1 cells when treated with peptide nucleic acid conjugate, with a 95% inhibition at 1 uM concentration. It shows potency against anthrax lethal toxin internalization (12,589.3 nM) and Regulator of G Protein Signaling (RGS) 4 (2,993.5 nM). The compound inhibits various GABA transporters, including GAT3 (41,200 nM) and GAT2 (>100,000 nM), impacting GABAergic neurotransmission. Additionally, it binds to Mycobacterium tuberculosis pantothenate synthetase, inducing structural changes in alpha-helix and beta-sheet regions. β-Alanine also inhibits human PAT1-mediated L-[3H]proline uptake with a Ki of 2,400,000 nM and has a pKa of 10.2. These bioactivities indicate its potential utility as a biochemical modulator in various therapeutic contexts..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	β-Alanine (3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotransmitter by activating glycine and GABA receptors.
Synonyms	beta-Alanine, 3-Aminopropanoic acid, 2-Carboxyethylamine

Chemical Properties

Molecular Weight	89.09
Formula	C₃H₇NO₂
Cas No.	107-95-9
Smiles	NCCC(O)=O
Relative Density.	1.437 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: < 10 mM(< means unknown), Sonication is recommended.

H2O: 100 mg/mL (1122.46 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	11.2246 mL	56.1230 mL	112.2460 mL	561.2302 mL
5 mM	2.2449 mL	11.2246 mL	22.4492 mL	112.2460 mL
10 mM	1.1225 mL	5.6123 mL	11.2246 mL	56.1230 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.5612 mL	2.8062 mL	5.6123 mL	28.0615 mL
50 mM	0.2245 mL	1.1225 mL	2.2449 mL	11.2246 mL
100 mM	0.1122 mL	0.5612 mL	1.1225 mL	5.6123 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc