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DKFZ-748 is a selective HDAC10 inhibitor and has a dose-dependent growth inhibitory effect on HeLa cells.
Pack Size | Price | Availability | Quantity |
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1 mg | $98 | In Stock | |
5 mg | $243 | In Stock |
Description | DKFZ-748 is a selective HDAC10 inhibitor and has a dose-dependent growth inhibitory effect on HeLa cells. |
In vitro | DKFZ-748 inhibits HeLa cell growth in a dose-dependent manner and induces HDAC acetylation in BE(2)-C cells (1–100 μM, 72 h), with significant effects observed only at the highest concentration (100 μM). DKFZ-748 also causes dose-dependent accumulation of N8-acetyl- and N1,8-diacetylspermidine[1]. |
Alias | DKFZ748 |
Molecular Weight | 329.39 |
Formula | C18H23N3O3 |
Cas No. | 2490709-68-5 |
Smiles | O=C(NCCN(C)CCCC(=O)NO)C1=CC=CC=2C=CC=CC21 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (242.87 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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