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Nicotinamide riboside

Name: Nicotinamide riboside
Brand: TargetMol
SKU: T13795
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T13795Cas No. 1341-23-7

Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.

Nicotinamide riboside

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Purity: 99.58%

Catalog No. T13795Cas No. 1341-23-7

Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.

Pack Size	Price	Availability	Quantity
5 mg	$50	In Stock
200 mg	$240	In Stock

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Purity:99.58%

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Product Introduction

Bioactivity

Description	Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.
In vitro	Nicotinamide riboside (NR) supplementation in mammalian cells and mouse tissues increases NAD(+) levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high-fat diet-induced metabolic abnormalities.
In vivo	The natural vitamin Nicotinamide riboside (NR) could be used as a nutritional supplement to ameliorate metabolic and age-related disorders characterized by defective mitochondrial function.

Chemical Properties

Molecular Weight	255.25
Formula	C₁₁H₁₅N₂O₅
Cas No.	1341-23-7
Smiles	O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)[N+]=2C=C(C(N)=O)C=CC2
Relative Density.	1.201g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (489.72 mM), Sonication is recommended.

H2O: 50 mg/mL (195.89 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9177 mL	19.5886 mL	39.1773 mL	195.8864 mL
5 mM	0.7835 mL	3.9177 mL	7.8355 mL	39.1773 mL
10 mM	0.3918 mL	1.9589 mL	3.9177 mL	19.5886 mL
20 mM	0.1959 mL	0.9794 mL	1.9589 mL	9.7943 mL
50 mM	0.0784 mL	0.3918 mL	0.7835 mL	3.9177 mL
100 mM	0.0392 mL	0.1959 mL	0.3918 mL	1.9589 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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