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(-)-Ketoconazole

Name: (-)-Ketoconazole
Brand: TargetMol
SKU: T13464L
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T13464LCas No. 142128-57-2

Alias (-)-R41400, (-)-R 41400, (-)-Ketoconazol

(-)-Ketoconazole is a potential mitochondrial CYP24A1 inhibitor and has antifungal activity against Aspergillus fumigatus.

(-)-Ketoconazole

🥰Excellent

Catalog No. T13464LAlias (-)-R41400, (-)-R 41400, (-)-KetoconazolCas No. 142128-57-2

(-)-Ketoconazole is a potential mitochondrial CYP24A1 inhibitor and has antifungal activity against Aspergillus fumigatus.

Pack Size	Price	Availability	Quantity
2 mg	$30	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	(-)-Ketoconazole is a potential mitochondrial CYP24A1 inhibitor and has antifungal activity against Aspergillus fumigatus.
Alias	(-)-R41400, (-)-R 41400, (-)-Ketoconazol

Chemical Properties

Molecular Weight	531.43
Formula	C₂₆H₂₈Cl₂N₄O₄
Cas No.	142128-57-2
Smiles	C([C@@]1(O[C@H](COC2=CC=C(C=C2)N3CCN(C(C)=O)CC3)CO1)C4=C(Cl)C=C(Cl)C=C4)N5C=CN=C5
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (56.45 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8817 mL	9.4086 mL	18.8172 mL	94.0858 mL
5 mM	0.3763 mL	1.8817 mL	3.7634 mL	18.8172 mL
10 mM	0.1882 mL	0.9409 mL	1.8817 mL	9.4086 mL
20 mM	0.0941 mL	0.4704 mL	0.9409 mL	4.7043 mL
50 mM	0.0376 mL	0.1882 mL	0.3763 mL	1.8817 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc