Shopping Cart

Remove All
Your shopping cart is currently empty

Alrestatin

Name: Alrestatin
Brand: TargetMol
SKU: T5195
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T5195Cas No. 51411-04-2

Alias AY-22284

Alrestatin (AY-22284) is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.

Alrestatin

🥰Excellent

Purity: 99.23%

Catalog No. T5195Alias AY-22284Cas No. 51411-04-2

Alrestatin (AY-22284) is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.

Pack Size	Price	Availability
5 mg	$38	In Stock
10 mg	$58	In Stock
25 mg	$92	In Stock
50 mg	$119	In Stock
100 mg	$197	In Stock
200 mg	$319	In Stock
1 mL x 10 mM (in DMSO)	$42	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.23%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Alrestatin (AY-22284) is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.
Synonyms	AY-22284

Chemical Properties

Molecular Weight	255.2256
Formula	C₁₄H₉NO₄
Cas No.	51411-04-2
Smiles	OC(=O)CN1C(=O)c2cccc3cccc(C1=O)c23
Relative Density.	1.511g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (97.95 mM), Sonication is recommended.

H2O: Insoluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9181 mL	19.5905 mL	39.1810 mL	195.9051 mL
5 mM	0.7836 mL	3.9181 mL	7.8362 mL	39.1810 mL
10 mM	0.3918 mL	1.9591 mL	3.9181 mL	19.5905 mL
20 mM	0.1959 mL	0.9795 mL	1.9591 mL	9.7953 mL
50 mM	0.0784 mL	0.3918 mL	0.7836 mL	3.9181 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc