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Oroxylin A 7-O-β-d-glucuronide

🥰Excellent
Catalog No. T3891Cas No. 36948-76-2
Alias Oroxylin A Glucoronide, Oroxylin A 7-O-beta-D-glucuronide

Oroxylin A 7-O-β-d-glucuronide and wogonoside should also be served as the chemical markers together with baicalin for the quality control of herbs and proprietary traditional Chinese medicine (PTCM) products of radix Scutellariae. Oroxylin A 7-O-glucuronide, Oroxin A, and Oroxin B can bind to the "stem" region of α-hemolysin (α-HL), when inhibiting the hemolytic activity of α-HL. Oroxylin A 7-O-glucuronide and 4', 5, 7-trihydroxy-6-methoxyflavone at a concentration of 100 microM inhibit 34 and 43% of total prolyl oligopeptidase (POP) activity, respectively.

Oroxylin A 7-O-β-d-glucuronide
Other Forms of Oroxylin A 7-O-β-d-glucuronide:
Oroxylin A 7-O-glucosideTN678236948-77-3
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Oroxylin A 7-O-β-d-glucuronide

🥰Excellent
Purity: 99.67%
Catalog No. T3891Alias Oroxylin A Glucoronide, Oroxylin A 7-O-beta-D-glucuronideCas No. 36948-76-2
Oroxylin A 7-O-β-d-glucuronide and wogonoside should also be served as the chemical markers together with baicalin for the quality control of herbs and proprietary traditional Chinese medicine (PTCM) products of radix Scutellariae. Oroxylin A 7-O-glucuronide, Oroxin A, and Oroxin B can bind to the "stem" region of α-hemolysin (α-HL), when inhibiting the hemolytic activity of α-HL. Oroxylin A 7-O-glucuronide and 4', 5, 7-trihydroxy-6-methoxyflavone at a concentration of 100 microM inhibit 34 and 43% of total prolyl oligopeptidase (POP) activity, respectively.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$80In StockIn Stock
5 mg$190In StockIn Stock
10 mg$278In StockIn Stock
25 mg$469In StockIn Stock
50 mg$689In StockIn Stock
100 mg$983In StockIn Stock
1 mL x 10 mM (in DMSO)$197In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.67%
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Product Introduction

Bioactivity
Description
Oroxylin A 7-O-β-d-glucuronide and wogonoside should also be served as the chemical markers together with baicalin for the quality control of herbs and proprietary traditional Chinese medicine (PTCM) products of radix Scutellariae. Oroxylin A 7-O-glucuronide, Oroxin A, and Oroxin B can bind to the "stem" region of α-hemolysin (α-HL), when inhibiting the hemolytic activity of α-HL. Oroxylin A 7-O-glucuronide and 4', 5, 7-trihydroxy-6-methoxyflavone at a concentration of 100 microM inhibit 34 and 43% of total prolyl oligopeptidase (POP) activity, respectively.
SynonymsOroxylin A Glucoronide, Oroxylin A 7-O-beta-D-glucuronide
Chemical Properties
Molecular Weight460.39
FormulaC22H20O11
Cas No.36948-76-2
SmilesCOc1c(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)cc2oc(cc(=O)c2c1O)-c1ccccc1
Relative Density.1.629 g/cm3 at 20℃
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (130.32 mM), Sonication is recommended.
Ethanol: Soluble
Pyridine, Methanol, etc.: Soluble
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.34 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1721 mL10.8604 mL21.7207 mL108.6036 mL
5 mM0.4344 mL2.1721 mL4.3441 mL21.7207 mL
10 mM0.2172 mL1.0860 mL2.1721 mL10.8604 mL
20 mM0.1086 mL0.5430 mL1.0860 mL5.4302 mL
50 mM0.0434 mL0.2172 mL0.4344 mL2.1721 mL
100 mM0.0217 mL0.1086 mL0.2172 mL1.0860 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

prolyl oligopeptidaseProlyl Endopeptidase (PREP)prolylPOPOroxylin A-7-O-glucuronideOroxylin A7OglucuronideOroxylin A 7-O-β-D-glucuronideOroxylin A 7-O-b-D-glucuronideOroxylin A 7 O glucuronideoligopeptidaseInhibitorinhibit
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