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UCK2 Inhibitor-2

🥰Excellent
Catalog No. T68498Cas No. 866842-71-9
Alias UCK2-IN-2

UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.

UCK2 Inhibitor-2

UCK2 Inhibitor-2

🥰Excellent
Purity: 99.25%
Catalog No. T68498Alias UCK2-IN-2Cas No. 866842-71-9
UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.
Pack SizePriceAvailabilityQuantity
25 mg$2,420 In Stock
50 mg$3,180 In Stock
100 mg$4,300 In Stock
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Purity:99.25%
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Product Introduction

Bioactivity
Description
UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.
Targets&IC50
UCK2 in K562 cells:3.8 μM
In vitro
UCK2 Inhibitor-2 (compound 20874830) inhibits UCK2 with an IC₅₀ of 3.8 μM, and at 50 μM, suppresses uridine salvage by 52% in K562 cells[1].
AliasUCK2-IN-2
Chemical Properties
Molecular Weight497.57
FormulaC28H23N3O4S
Cas No.866842-71-9
SmilesO=C(O)C=1C=CC=C(C1)NC(=O)CSC=2N=C(N=C3OC=4C(=CC=CC4CC32)C)C=5C=CC(=CC5)C
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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