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UCK2 Inhibitor-2

Name: UCK2 Inhibitor-2
Brand: TargetMol
SKU: T68498
Price: 545 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T68498Cas No. 866842-71-9

Alias UCK2-IN-2

UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.

UCK2 Inhibitor-2

🥰Excellent

Purity: 99.25%

Catalog No. T68498Alias UCK2-IN-2Cas No. 866842-71-9

UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$545	In Stock	In Stock
5 mg	$1,190	In Stock	In Stock
10 mg	$1,630	-	In Stock
25 mg	$2,420	-	In Stock
50 mg	$3,180	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.25%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.
Targets&IC50	UCK2 in K562 cells:3.8 μM
In vitro	UCK2 Inhibitor-2 (compound 20874830) inhibits UCK2 with an IC₅₀ of 3.8 μM, and at 50 μM, suppresses uridine salvage by 52% in K562 cells[1].
Synonyms	UCK2-IN-2

Chemical Properties

Molecular Weight	497.57
Formula	C₂₈H₂₃N₃O₄S
Cas No.	866842-71-9
Smiles	O=C(O)C=1C=CC=C(C1)NC(=O)CSC=2N=C(N=C3OC=4C(=CC=CC4CC32)C)C=5C=CC(=CC5)C
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc