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Bohemine

Name: Bohemine
Brand: TargetMol
SKU: T2029
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T2029Cas No. 189232-42-6

Bohemine is a cyclin-dependent kinase inhibitor.

Bohemine

🥰Excellent

Purity: 99.53%

Catalog No. T2029Cas No. 189232-42-6

Bohemine is a cyclin-dependent kinase inhibitor.

Pack Size	Price	Availability
10 mg	$35	In Stock
25 mg	$71	In Stock
50 mg	$108	In Stock
100 mg	$163	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.53%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Bohemine is a cyclin-dependent kinase inhibitor.
Targets&IC50	CDK2-CyclinA:83 μM (IC50), CDK2-CyclinE:4.6 μM (IC50), CDK9-CyclinT1:2.7 μM (IC50), ERK2:52 μM (IC50)

Chemical Properties

Molecular Weight	340.42
Formula	C₁₈H₂₄N₆O
Cas No.	189232-42-6
Smiles	CC(C)n1cnc2c(NCc3ccccc3)nc(NCCCO)nc12
Relative Density.	1.27 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (146.88 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9375 mL	14.6877 mL	29.3755 mL	146.8774 mL
5 mM	0.5875 mL	2.9375 mL	5.8751 mL	29.3755 mL
10 mM	0.2938 mL	1.4688 mL	2.9375 mL	14.6877 mL
20 mM	0.1469 mL	0.7344 mL	1.4688 mL	7.3439 mL
50 mM	0.0588 mL	0.2938 mL	0.5875 mL	2.9375 mL
100 mM	0.0294 mL	0.1469 mL	0.2938 mL	1.4688 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc