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(S)-AK-242
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Catalog No. T80678Cas No. 243984-10-3
Alias AK-242 (S enantiomer), (S)-Resatorvid, (-)-Resatorvid, (-)-AK-242
(S)-AK-242 ((S)-Resatorvid) is a cytokine inhibitor used in the treatment of heart disease, autoimmune disease, and inflammatory disease.
(S)-AK-242
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Purity: 99.86%
Catalog No. T80678Alias AK-242 (S enantiomer), (S)-Resatorvid, (-)-Resatorvid, (-)-AK-242Cas No. 243984-10-3
(S)-AK-242 ((S)-Resatorvid) is a cytokine inhibitor used in the treatment of heart disease, autoimmune disease, and inflammatory disease.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $37 | In Stock | In Stock | |
| 5 mg | $81 | In Stock | In Stock | |
| 10 mg | $150 | In Stock | In Stock | |
| 25 mg | $315 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.86%
Appearance:Solid
Color:Yellow
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Product Introduction
(S)-AK-242 AI Summary
(S)-AK-242 exhibits bioactivities related to anti-inflammatory properties, demonstrating inhibition of nitric oxide, TNFalpha, and IL6 production in mouse RAW264.7 cells in response to lipopolysaccharide (LPS) stimulation with varying IC50 values. This activity suggests that (S)-AK-242 may have potential anti-inflammatory effects by modulating the release of these pro-inflammatory mediators. Additionally, (S)-AK-242 has been tested for its antiviral activity against SARS-CoV-2. The assay involved measuring the inhibition of SARS-CoV-2 induced cytotoxicity in VERO-6 cells at a concentration of 10 µM after 48 hours of exposure. Results indicated an IC50 value greater than 20,000.0 nM, suggesting a relatively weak antiviral effect against SARS-CoV-2 at the tested concentration and duration..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | (S)-AK-242 ((S)-Resatorvid) is a cytokine inhibitor used in the treatment of heart disease, autoimmune disease, and inflammatory disease. |
| Synonyms | AK-242 (S enantiomer), (S)-Resatorvid, (-)-Resatorvid, (-)-AK-242 |
| Molecular Weight | 361.82 |
| Formula | C15H17ClFNO4S |
| Cas No. | 243984-10-3 |
| Smiles | S(NC1=C(Cl)C=C(F)C=C1)(=O)(=O)[C@@H]2C(C(OCC)=O)=CCCC2 |
| Relative Density. | 1.39 g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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