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(R)-DRF053 dihydrochloride

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Catalog No. T23224Cas No. 1241675-76-2

cdk/CK1 inhibitor,potent and ATP-competitive

(R)-DRF053 dihydrochloride

(R)-DRF053 dihydrochloride

😃Good
Catalog No. T23224Cas No. 1241675-76-2
cdk/CK1 inhibitor,potent and ATP-competitive
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$4,78035 days35 days
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Expected start date of shipmentUSA Warehouse [1-2 days] Global Warehouse [5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
cdk/CK1 inhibitor,potent and ATP-competitive
Targets&IC50
CDK1-cyclinB1:220 nM, CK1:14 nM, CDK5-p25:80 nM
Chemical Properties
Molecular Weight490.43
FormulaC23H29Cl2N7O
Cas No.1241675-76-2
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: <49.04 mg/mL, Sonication is recommended.
DMSO: <49.04 mg/mL, Sonication is recommended.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

DRF 053 DihydrochlorideDRF-053DRF 053(R) DRF053 dihydrochloride(R)DRF053 dihydrochlorideDRF053 DihydrochlorideDRF053DRF-053 Dihydrochloride(R)-DRF-053 dihydrochloride
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