Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Wu-5 is a potent USP10 inhibitor that inhibits FLT3 and AMPK pathways, promoting the breakdown of FLT3-ITD and inducing apoptosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 76.00 | |
5 mg | In stock | $ 197.00 | |
10 mg | In stock | $ 313.00 | |
25 mg | In stock | $ 628.00 | |
50 mg | In stock | $ 997.00 | |
100 mg | In stock | $ 1,330.00 | |
500 mg | In stock | $ 2,690.00 |
Description | Wu-5 is a potent USP10 inhibitor that inhibits FLT3 and AMPK pathways, promoting the breakdown of FLT3-ITD and inducing apoptosis. |
In vitro |
Wu-5 (10 μM; 24, 48, 72 h) selectively induces death in FLT3-ITD positive AML cells[1]. Wu-5 (1, 2.5, 5 μM; 24, 48 h) induces apoptosis in FLT3-ITD positive AML cells in a time- and concentration-dependent manner[1]. Wu-5 (5 μM; 24 h) induces degradation of FLT3-ITD through the proteasome pathway[1]. |
Molecular Weight | 351.33 |
Formula | C15H13NO7S |
CAS No. | 2630378-05-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL (56.93 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Wu-5 2630378-05-9 Cell Cycle/Checkpoint DNA Damage/DNA Repair Ubiquitination DUB Wu5 inhibitor inhibit