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Cefotiam hydrochloride

Name: Cefotiam hydrochloride
Brand: TargetMol
SKU: T1616
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T1616Cas No. 66309-69-1

Alias SCE-963 hydrochloride, Pansporine, Pansporin, Halospor, Cefotiam dihydrochloride

Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.

Cefotiam hydrochloride

😃Good

Purity: 98.23%

Catalog No. T1616Alias SCE-963 hydrochloride, Pansporine, Pansporin, Halospor, Cefotiam dihydrochlorideCas No. 66309-69-1

Pack Size	Price	Availability
10 mg	$39	Backorder
50 mg	$55	Backorder
100 mg	$80	Backorder
200 mg	$118	Backorder
500 mg	$198	Backorder

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Purity:98.23%

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Product Introduction

Bioactivity

Description

Synonyms

SCE-963 hydrochloride, Pansporine, Pansporin, Halospor, Cefotiam dihydrochloride

Chemical Properties

Molecular Weight	598.60
Formula	C₁₈H₂₃N₉O₄S₃.2HCl
Cas No.	66309-69-1
Smiles	Cl.Cl.[H][C@]12SCC(CSc3nnnn3CCN(C)C)=C(N1C(=O)[C@H]2NC(=O)Cc1csc(N)n1)C(O)=O
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50.00 mg/mL (83.53 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6706 mL	8.3528 mL	16.7056 mL	83.5282 mL
5 mM	0.3341 mL	1.6706 mL	3.3411 mL	16.7056 mL
10 mM	0.1671 mL	0.8353 mL	1.6706 mL	8.3528 mL
20 mM	0.0835 mL	0.4176 mL	0.8353 mL	4.1764 mL
50 mM	0.0334 mL	0.1671 mL	0.3341 mL	1.6706 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc