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HCAIX-IN-2

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Catalog No. T62755Cas No. 2389034-45-9

HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase, targeting hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).

HCAIX-IN-2

HCAIX-IN-2

😃Good
Catalog No. T62755Cas No. 2389034-45-9
HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase, targeting hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$1,5206-8 weeks6-8 weeks
50 mg$1,9806-8 weeks6-8 weeks
100 mg$2,5006-8 weeks6-8 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase, targeting hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).
Targets&IC50
CA IX (human):24.6 nM (Ki), CA I:2481 nM (Ki), CA II (human):456.2 nM (Ki), CA XII (human):45.3 nM (Ki)
Chemical Properties
Molecular Weight452.45
FormulaC19H16N8O4S
Cas No.2389034-45-9
SmilesC(NN=CC=1C=CN=CC1)(=O)C=2N3C(N(N2)C4=CC=C(S(N)(=O)=O)C=C4)=NC(C)=CC3=O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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