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IDO-IN-3

Name: IDO-IN-3
Brand: TargetMol
SKU: T11617
Rating: 4.5 (1 reviews)

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Catalog No. T11617Cas No. 2070018-30-1

IDO-IN-3 is a potent inhibitor of indoleamine 2,3-dioxygenase (IDO), with an IC50 value of 290 nM.

IDO-IN-3

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Catalog No. T11617Cas No. 2070018-30-1

IDO-IN-3 is a potent inhibitor of indoleamine 2,3-dioxygenase (IDO), with an IC50 value of 290 nM.

Pack Size	Price	Availability
2 mg	$227	6-8 weeks
25 mg	$1,370	6-8 weeks
50 mg	$1,790	6-8 weeks

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Product Introduction

Bioactivity

Description	IDO-IN-3 is a potent inhibitor of indoleamine 2,3-dioxygenase (IDO), with an IC50 value of 290 nM.
Targets&IC50	IDO:290 nM, IDO:98 nM (in HeLa cell)
In vitro	IDO-IN-3 is a potent (HeLa IC50=98 nM) inhibitor of IDO.

Chemical Properties

Molecular Weight	359.15
Formula	C₁₁H₁₂BrFN₆O₂
Cas No.	2070018-30-1
Relative Density.	1.86 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (76.57 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7844 mL	13.9218 mL	27.8435 mL	139.2176 mL
5 mM	0.5569 mL	2.7844 mL	5.5687 mL	27.8435 mL
10 mM	0.2784 mL	1.3922 mL	2.7844 mL	13.9218 mL
20 mM	0.1392 mL	0.6961 mL	1.3922 mL	6.9609 mL
50 mM	0.0557 mL	0.2784 mL	0.5569 mL	2.7844 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc