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Oxybutynin chloride

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Catalog No. T1049Cas No. 1508-65-2
Alias Oxybutynin hydrochloride, Oxybutynin HCl

Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor.

Oxybutynin chloride

Oxybutynin chloride

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Purity: 99.27%
Catalog No. T1049Alias Oxybutynin hydrochloride, Oxybutynin HClCas No. 1508-65-2
Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mg$29In StockIn Stock
500 mg$58-In Stock
1 g$85-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.27%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor.
In vitro
Oxybutynin relieves urinary and bladder difficulties, including frequent urination and inability to control urination (urge incontinence), by decreasing muscle spasms of the bladder. Oxybutynin competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor. [1] Oxybutynin also has direct spasmolytic effects on bladder smooth muscle as a calcium antagonist and local anesthetic, but at concentrations far above those used clinically. [2]
SynonymsOxybutynin hydrochloride, Oxybutynin HCl
Chemical Properties
Molecular Weight393.96
FormulaC22H32ClNO3
Cas No.1508-65-2
SmilesC(C(=O)OCC#CCN(CC)CC)(c1ccccc1)(C1CCCCC1)O.Cl
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 73 mg/mL (185.3 mM), Sonication is recommended.
DMSO: 55 mg/mL (139.61 mM), Sonication is recommended.
H2O: 4 mg/mL (10.15 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.08 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
H2O/DMSO/Ethanol
1mg5mg10mg50mg
1 mM2.5383 mL12.6916 mL25.3833 mL126.9164 mL
5 mM0.5077 mL2.5383 mL5.0767 mL25.3833 mL
10 mM0.2538 mL1.2692 mL2.5383 mL12.6916 mL
DMSO/Ethanol
1mg5mg10mg50mg
20 mM0.1269 mL0.6346 mL1.2692 mL6.3458 mL
50 mM0.0508 mL0.2538 mL0.5077 mL2.5383 mL
100 mM0.0254 mL0.1269 mL0.2538 mL1.2692 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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