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Urolithin M5
🥰Excellent
Catalog No. T84318Cas No. 91485-02-8
Alias Decarboxyellagic acid
Urolithin M5 (Decarboxyellagic acid) is a neuraminidase inhibitor isolated from olive leaves with antiviral and anticancer and antitumor activities. Urolithin M5 can be used to study influenza A virus infection and SARS-CoV-2 infection.
Urolithin M5
🥰Excellent
Purity: 95.32%
Catalog No. T84318Alias Decarboxyellagic acidCas No. 91485-02-8
Urolithin M5 (Decarboxyellagic acid) is a neuraminidase inhibitor isolated from olive leaves with antiviral and anticancer and antitumor activities. Urolithin M5 can be used to study influenza A virus infection and SARS-CoV-2 infection.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $56 | In Stock | In Stock | |
| 5 mg | $163 | In Stock | In Stock | |
| 10 mg | $243 | In Stock | In Stock | |
| 25 mg | $397 | In Stock | In Stock | |
| 50 mg | $598 | In Stock | In Stock | |
| 100 mg | $848 | - | In Stock | |
| 200 mg | $1,130 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:95.32%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Urolithin M5 (Decarboxyellagic acid) is a neuraminidase inhibitor isolated from olive leaves with antiviral and anticancer and antitumor activities. Urolithin M5 can be used to study influenza A virus infection and SARS-CoV-2 infection. |
| Targets&IC50 | MDCK cells:CC50=227.4 μM, Virus:3.74~16.51 μM |
| In vitro | The cytotoxicity of urolithin M5 was initially assessed using the MTT assay on MDCK cells. Urolithin M5 had a CC50 value of 227.4 μM. [1] 25 μM urolithin M5 inhibited all virus growth, urolithin M5 was the most effective compound, with an IC50 ranging from 3.74 to 16.51 μM. [1] |
| In vivo | Specific-pathogen-free female BALB/c mice weighing 16 to 18 g. A total of 200 mg/kg/d urolithin M5 treatment improved the survival rate to 50%, which was significantly higher than the vehicle group. These results indicated that 200 mg/kg/d urolithin M5 had a protective effect on PR8-infected mice. [1] |
| Synonyms | Decarboxyellagic acid |
| Molecular Weight | 276.2 |
| Formula | C13H8O7 |
| Cas No. | 91485-02-8 |
| Smiles | O=C1OC=2C(O)=C(O)C=CC2C3=C(O)C(O)=C(O)C=C13 |
| Relative Density. | 1.894 g/cm3 (Predicted) |
| Color | Yellow |
| Appearance | Solid |
Storage & Solubility Information
| Storage | store at low temperature,keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 15 mg/mL (54.31 mM), Sonication and heating are recommended. DMSO: 62 mg/mL (224.48 mM), Sonication is recommended.  | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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