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NC03

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Catalog No. T71797Cas No. 568558-66-7
Alias NC 03

NC03 is an effective PI4K2A inhibitor that reduces intracellular PI4P pools in the Golgi apparatus and endosomes, with PI4K2A being the primary source of PI4P. NC03 may be utilised in cancer research.

NC03

NC03

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Purity: 99.73%
Catalog No. T71797Alias NC 03Cas No. 568558-66-7
NC03 is an effective PI4K2A inhibitor that reduces intracellular PI4P pools in the Golgi apparatus and endosomes, with PI4K2A being the primary source of PI4P. NC03 may be utilised in cancer research.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$107-In Stock
5 mg$263-In Stock
10 mg$413-In Stock
25 mg$793-In Stock
50 mg$1,130-In Stock
1 mL x 10 mM (in DMSO)$266-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.73%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
NC03 is an effective PI4K2A inhibitor that reduces intracellular PI4P pools in the Golgi apparatus and endosomes, with PI4K2A being the primary source of PI4P. NC03 may be utilised in cancer research.
SynonymsNC 03
Chemical Properties
Molecular Weight459.47
FormulaC21H21N3O7S
Cas No.568558-66-7
SmilesO=C(NC1=CC=C2OCCOC2=C1)CSC3=NN=C(O3)C=4C=C(OC)C(OC)=C(OC)C4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (174.11 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+90% Corn Oil: 3.3 mg/mL (7.18 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1764 mL10.8821 mL21.7642 mL108.8210 mL
5 mM0.4353 mL2.1764 mL4.3528 mL21.7642 mL
10 mM0.2176 mL1.0882 mL2.1764 mL10.8821 mL
20 mM0.1088 mL0.5441 mL1.0882 mL5.4411 mL
50 mM0.0435 mL0.2176 mL0.4353 mL2.1764 mL
100 mM0.0218 mL0.1088 mL0.2176 mL1.0882 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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