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DMA

🥰Excellent
Catalog No. T18981Cas No. 188860-26-6

DMA is a fluorescent agent (λex=340 nm, λem=478 nm).

DMA

DMA

🥰Excellent
Purity: 98.27%
Catalog No. T18981Cas No. 188860-26-6
DMA is a fluorescent agent (λex=340 nm, λem=478 nm).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$34In StockIn Stock
10 mg$48In StockIn Stock
25 mg$107In StockIn Stock
50 mg$185In StockIn Stock
100 mg$350In StockIn Stock
1 mL x 10 mM (in DMSO)$38In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:98.27%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
DMA is a fluorescent agent (λex=340 nm, λem=478 nm).
Targets&IC50
HeLa cells:3.4 μM (IC50), MCF-7 cells:5.3 μM (IC50)
In vitro
In the case of MCF7, the IC50 is observed at 5.3 μM for DMA. The IC50 determined in the case of HeLa is 3.4 μM for DMA.
Chemical Properties
Molecular Weight468.55
FormulaC27H28N6O2
Cas No.188860-26-6
SmilesCOc1ccc(cc1OC)-c1nc2cc(ccc2[nH]1)-c1nc2cc(ccc2[nH]1)N1CCN(C)CC1
Relative Density.1.292 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 13 mg/mL (27.75 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1342 mL10.6712 mL21.3424 mL106.7122 mL
5 mM0.4268 mL2.1342 mL4.2685 mL21.3424 mL
10 mM0.2134 mL1.0671 mL2.1342 mL10.6712 mL
20 mM0.1067 mL0.5336 mL1.0671 mL5.3356 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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