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Anagrelide

Name: Anagrelide
Brand: TargetMol
SKU: T0160
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0160Cas No. 68475-42-3

Alias Xagrid, Anagrelidum, Anagrelida

Anagrelide (Xagrid) is a Platelet-reducing Agent. The mechanism of action of anagrelide is as a Phosphodiesterase 3 Inhibitor. The physiologic effect of anagrelide is by means of Decreased Platelet Production.

Anagrelide

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Purity: 99.53%

Catalog No. T0160Alias Xagrid, Anagrelidum, AnagrelidaCas No. 68475-42-3

Pack Size	Price	Availability
2 mg	$31	In Stock
5 mg	$48	In Stock
10 mg	$67	In Stock
25 mg	$107	In Stock
50 mg	$156	In Stock
100 mg	$229	In Stock
500 mg	$592	In Stock
1 mL x 10 mM (in DMSO)	$53	In Stock

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Purity:99.53%

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COA HNMR

Product Introduction

Bioactivity

Description	Anagrelide (Xagrid) is a Platelet-reducing Agent. The mechanism of action of anagrelide is as a Phosphodiesterase 3 Inhibitor. The physiologic effect of anagrelide is by means of Decreased Platelet Production.
Synonyms	Xagrid, Anagrelidum, Anagrelida

Chemical Properties

Molecular Weight	256.09
Formula	C₁₀H₇Cl₂N₃O
Cas No.	68475-42-3
Smiles	ClC1=C2C(NC=3N(C2)CC(=O)N3)=CC=C1Cl
Relative Density.	1.77g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mM, Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9049 mL	19.5244 mL	39.0488 mL	195.2439 mL
5 mM	0.7810 mL	3.9049 mL	7.8098 mL	39.0488 mL
10 mM	0.3905 mL	1.9524 mL	3.9049 mL	19.5244 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc