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Vigabatrin Hydrochloride

Name: Vigabatrin Hydrochloride
Brand: TargetMol
SKU: T0128L
Rating: 4.5 (1 reviews)

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Catalog No. T0128LCas No. 1391054-02-6

Alias γ-Vinyl-GABA hydrochloride

Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA), which irreversibly inhibits the catabolism of GABA by GABA transaminase.

Vigabatrin Hydrochloride

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Catalog No. T0128LAlias γ-Vinyl-GABA hydrochlorideCas No. 1391054-02-6

Pack Size	Price	Availability	Quantity
2 mg	$53	5 days
1 mL x 10 mM (in DMSO)	$68	7-10 days

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Product Introduction

Bioactivity

Description	Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA), which irreversibly inhibits the catabolism of GABA by GABA transaminase.
Synonyms	γ-Vinyl-GABA hydrochloride

Chemical Properties

Molecular Weight	165.62
Formula	C₆H₁₁NO₂·HCl
Cas No.	1391054-02-6
Smiles	Cl.NC(CCC(O)=O)C=C
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 27.5 mg/mL (166.04 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.0379 mL	30.1896 mL	60.3792 mL	301.8959 mL
5 mM	1.2076 mL	6.0379 mL	12.0758 mL	60.3792 mL
10 mM	0.6038 mL	3.0190 mL	6.0379 mL	30.1896 mL
20 mM	0.3019 mL	1.5095 mL	3.0190 mL	15.0948 mL
50 mM	0.1208 mL	0.6038 mL	1.2076 mL	6.0379 mL
100 mM	0.0604 mL	0.3019 mL	0.6038 mL	3.0190 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc