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Anti-Influenza agent 4

Name: Anti-Influenza agent 4
Brand: TargetMol
SKU: T72037
Price: 55 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T72037Cas No. 522625-85-0

Anti-Influenza agent 4 is a potent and selective inhibitor of the influenza virus, effectively inhibiting the A/Parma and A/Roma strains with EC50s of 62 nM and 150 nM, respectively.

Anti-Influenza agent 4

🥰Excellent

Purity: 98.95%

Catalog No. T72037Cas No. 522625-85-0

Anti-Influenza agent 4 is a potent and selective inhibitor of the influenza virus, effectively inhibiting the A/Parma and A/Roma strains with EC50s of 62 nM and 150 nM, respectively.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$55	In Stock	In Stock
5 mg	$123	In Stock	In Stock
10 mg	$195	In Stock	In Stock
25 mg	$453	In Stock	In Stock
50 mg	$668	In Stock	In Stock
100 mg	$949	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:98.95%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Anti-Influenza agent 4 is a potent and selective inhibitor of the influenza virus, effectively inhibiting the A/Parma and A/Roma strains with EC50s of 62 nM and 150 nM, respectively.
Targets&IC50	A/Roma:150±0.07 nM, A/Roma:62±0.02 nM
In vitro	Anti influenza agent 4 (compound 5) (0-500 μM; 24 and 48 hours) showed low cytotoxicity in Madin-Darby canine kidney cells.[1] In hemolytic inhibition assay anti influenza agent 4 showed an IC50 of 244 nM and 230.7 nM against influenza strains A/Roma and A/Parma, respectively.[1]

Chemical Properties

Molecular Weight	386.42
Formula	C₁₉H₁₈N₂O₅S
Cas No.	522625-85-0
Smiles	S(NCC1=CC=CO1)(=O)(=O)C2=CC(NC(=O)C3=CC=C(OC)C=C3)=CC=C2
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (116.45 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5879 mL	12.9393 mL	25.8786 mL	129.3929 mL
5 mM	0.5176 mL	2.5879 mL	5.1757 mL	25.8786 mL
10 mM	0.2588 mL	1.2939 mL	2.5879 mL	12.9393 mL
20 mM	0.1294 mL	0.6470 mL	1.2939 mL	6.4696 mL
50 mM	0.0518 mL	0.2588 mL	0.5176 mL	2.5879 mL
100 mM	0.0259 mL	0.1294 mL	0.2588 mL	1.2939 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc