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Etidocaine

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Catalog No. T31716LCas No. 36637-18-0

Etidocaine is an amino acidamide that acts as a local anesthetic with fast onset and long-acting properties.

Etidocaine

Etidocaine

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Purity: 99.99%
Catalog No. T31716LCas No. 36637-18-0
Etidocaine is an amino acidamide that acts as a local anesthetic with fast onset and long-acting properties.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$117In StockIn Stock
5 mg$262In StockIn Stock
10 mg$387In StockIn Stock
25 mg$592In StockIn Stock
50 mg$828In StockIn Stock
100 mg$1,110In StockIn Stock
500 mg$2,230-In Stock
1 mL x 10 mM (in DMSO)$231In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.99%
Appearance:Solid
Color:White
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Product Introduction

Etidocaine AI Summary
Etidocaine shows a range of bioactivities, notably influencing liver enzymes by increasing alkaline phosphatase, serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), lactate dehydrogenase (LDH), and gamma-glutamyl transferase (GGT), indicating potential effects on liver function. It inhibits the entry of the Ebola virus with an AC50 of 14125.4 nM and an Ac50 of 14.13 µM, and affects nuclear area and viability in VEGF-stimulated ADSC/ECFC co-culture assays with an IC50 of 10000.0 nM. In insulin secretion assays from INS-1E cells (IC50 = 33330.0 nM) and GLP1 secretion assays from STC-1 and NCI-H716 cells (IC50 = 40000.0 nM), it demonstrates moderate activity. Additionally, Etidocaine exhibits low antiviral activity against SARS-CoV-2 based on various assays, showing minimal inhibition in Vero E6 and Caco-2 cells and an IC50 value higher than 20,000 nM. It also demonstrates 14.91% inhibition of SARS-CoV-2 3CL-Pro protease at 20 µM. Furthermore, it exhibits minimal inhibition of human HDAC6 enzyme activity with inhibition rates of -12.37% and -6.64% in enzymatic assays..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Etidocaine is an amino acidamide that acts as a local anesthetic with fast onset and long-acting properties.
Chemical Properties
Molecular Weight276.42
FormulaC17H28N2O
Cas No.36637-18-0
SmilesN(C(C(N(CCC)CC)CC)=O)C1=C(C)C=CC=C1C
Relative Density.0.993 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (180.88 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6177 mL18.0884 mL36.1768 mL180.8842 mL
5 mM0.7235 mL3.6177 mL7.2354 mL36.1768 mL
10 mM0.3618 mL1.8088 mL3.6177 mL18.0884 mL
20 mM0.1809 mL0.9044 mL1.8088 mL9.0442 mL
50 mM0.0724 mL0.3618 mL0.7235 mL3.6177 mL
100 mM0.0362 mL0.1809 mL0.3618 mL1.8088 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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