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BMS-561392

Name: BMS-561392
Brand: TargetMol
SKU: T30531
Rating: 4.5 (1 reviews)

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Catalog No. T30531Cas No. 611227-74-8

Alias DPC-333, DPC333, DPC 333, BMS561392, BMS 561392

BMS-561392 (DPC333) is a tumor necrosis factor-α ( TNF-α) Invertase inhibitor.

BMS-561392

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Purity: 99.16%

Catalog No. T30531Alias DPC-333, DPC333, DPC 333, BMS561392, BMS 561392Cas No. 611227-74-8

BMS-561392 (DPC333) is a tumor necrosis factor-α ( TNF-α) Invertase inhibitor.

Pack Size	Price	Availability	Quantity
25 mg	$1,154	1-2 weeks
1 mL x 10 mM (in DMSO)	$529	1-2 weeks

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Batch Information

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Purity:99.16%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	BMS-561392 (DPC333) is a tumor necrosis factor-α ( TNF-α) Invertase inhibitor.
Synonyms	DPC-333, DPC333, DPC 333, BMS561392, BMS 561392

Chemical Properties

Molecular Weight	476.57
Formula	C₂₇H₃₂N₄O₄
Cas No.	611227-74-8
Smiles	N[C@@]1(C(=O)N([C@@H](C(NO)=O)CC(C)C)CC1)C2=CC=C(OCC=3C4=C(N=C(C)C3)C=CC=C4)C=C2
Relative Density.	1.253 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (94.42 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0983 mL	10.4916 mL	20.9833 mL	104.9164 mL
5 mM	0.4197 mL	2.0983 mL	4.1967 mL	20.9833 mL
10 mM	0.2098 mL	1.0492 mL	2.0983 mL	10.4916 mL
20 mM	0.1049 mL	0.5246 mL	1.0492 mL	5.2458 mL
50 mM	0.0420 mL	0.2098 mL	0.4197 mL	2.0983 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc