Popular Searches
Diphenyleneiodonium chlorideEpacadostatGilteritinibDinaciclibRo-3306
TargetMol | Star Product
Wikimole
TargetMol | New Product
New Product
TargetMol | Compound Library
Compound Library
Contact UsQuotation
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

Trimethobenzamide hydrochloride

🥰Excellent
Catalog No. T5009Cas No. 554-92-7
Alias Tribenzagan Hydrochloride, Ro 2-9578

Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.

Trimethobenzamide hydrochloride
Other Forms of Trimethobenzamide hydrochloride:

Trimethobenzamide hydrochloride

🥰Excellent
Purity: 99.52%
Catalog No. T5009Alias Tribenzagan Hydrochloride, Ro 2-9578Cas No. 554-92-7
Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.
Pack SizePriceAvailabilityQuantity
25 mg$39In Stock
50 mg$54In Stock
100 mg$81In Stock
500 mg$166In Stock
1 mL x 10 mM (in DMSO)$39In Stock
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Batch Information

Select Batch
Purity:99.52%
Contact us for more batch information

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity
Description
Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.
In vitro
Trimethobenzamide, a (non-phenothiazine) benzamide antiemetic, centrally blocks D2 receptors, inhibiting the medullary chemoreceptor trigger zone by obstructing emetic impulses to the vomiting center.
In vivo
Trimethobenzamide exhibits an oral bioavailability ranging from 60% to 100%, with a peak time of approximately 45 minutes post-oral administration. When administered intramuscularly (I.M.), the peak time is around 30 minutes.
SynonymsTribenzagan Hydrochloride, Ro 2-9578
Chemical Properties
Molecular Weight424.92
FormulaC21H29ClN2O5
Cas No.554-92-7
SmilesCl.COc1cc(cc(OC)c1OC)C(=O)NCc1ccc(OCCN(C)C)cc1
Relative Density.1.131g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (235.34 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3534 mL11.7669 mL23.5338 mL117.6692 mL
5 mM0.4707 mL2.3534 mL4.7068 mL23.5338 mL
10 mM0.2353 mL1.1767 mL2.3534 mL11.7669 mL
20 mM0.1177 mL0.5883 mL1.1767 mL5.8835 mL
50 mM0.0471 mL0.2353 mL0.4707 mL2.3534 mL
100 mM0.0235 mL0.1177 mL0.2353 mL1.1767 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Trimethobenzamide hydrochlorideTrimethobenzamide HydrochlorideTrimethobenzamideInhibitorinhibitInfluenzaVirusInfluenza VirusDopamineReceptorDopamine ReceptorDopamineD2
Related Tags: buy Trimethobenzamide hydrochloride | purchase Trimethobenzamide hydrochloride | Trimethobenzamide hydrochloride cost | order Trimethobenzamide hydrochloride | Trimethobenzamide hydrochloride chemical structure | Trimethobenzamide hydrochloride in vivo | Trimethobenzamide hydrochloride in vitro | Trimethobenzamide hydrochloride formula | Trimethobenzamide hydrochloride molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.