store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BCAT-IN-2 is an orally active and selective inhibitor of mitochondrial branched-chain aminotransferase (BCATm), inhibits BCATm and BCATc, and is used in obesity and dyslipidemia.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 116.00 | |
5 mg | In stock | $ 289.00 | |
10 mg | In stock | $ 455.00 | |
25 mg | In stock | $ 953.00 | |
50 mg | In stock | $ 1,490.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 318.00 |
Description | BCAT-IN-2 is an orally active and selective inhibitor of mitochondrial branched-chain aminotransferase (BCATm), inhibits BCATm and BCATc, and is used in obesity and dyslipidemia. |
Targets&IC50 | BCAT (rat, mitochondrial):7.39 (pIC50), BCAT (rat, cytosolic):6.6 (pIC50) |
In vitro | BCAT-IN-2 inhibits BCATm in primary human adipocytes, with a pIC50 of 6.5[1]. |
In vivo | BCAT-IN-2 (5 mg/kg, po; 1 mg/kg, iv) exhibits favorable pharmacokinetic parameters in mice[1]. |
Molecular Weight | 377.776 |
Formula | C17H14ClF2N5O |
CAS No. | 1800024-45-6 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (79.41 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BCAT-IN-2 1800024-45-6 Others BCATIN2 BCAT IN 2 inhibitor inhibit