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(S)-Monastrol

Name: (S)-Monastrol
Brand: TargetMol
SKU: T4649
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T4649Cas No. 254753-54-3

Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.

(S)-Monastrol

😃Good

Catalog No. T4649Cas No. 254753-54-3

Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.

Pack Size	Price	Availability	Quantity
10 mg	$862	35 days

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description

Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.

Chemical Properties

Molecular Weight	292.35
Formula	C₁₄H₁₆N₂O₃S
Cas No.	254753-54-3
Relative Density.	1.34g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 33 mg/mL (112.88 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4206 mL	17.1028 mL	34.2056 mL	171.0279 mL
5 mM	0.6841 mL	3.4206 mL	6.8411 mL	34.2056 mL
10 mM	0.3421 mL	1.7103 mL	3.4206 mL	17.1028 mL
20 mM	0.1710 mL	0.8551 mL	1.7103 mL	8.5514 mL
50 mM	0.0684 mL	0.3421 mL	0.6841 mL	3.4206 mL
100 mM	0.0342 mL	0.1710 mL	0.3421 mL	1.7103 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc