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Bekanamycin

Name: Bekanamycin
Brand: TargetMol
SKU: T8118
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T8118Cas No. 4696-76-8

Alias Kanamycin B

Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic extracted from Streptomyces kanamyceticus, which inhibits a range of Gram-positive and Gram-negative bacteria.

Bekanamycin

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Purity: 99.97%

Catalog No. T8118Alias Kanamycin BCas No. 4696-76-8

Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic extracted from Streptomyces kanamyceticus, which inhibits a range of Gram-positive and Gram-negative bacteria.

Pack Size	Price	Availability	Quantity
50 mg	$29	In Stock

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Purity:99.97%

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Product Introduction

Bioactivity

Description	Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic extracted from Streptomyces kanamyceticus, which inhibits a range of Gram-positive and Gram-negative bacteria.
Targets&IC50	HEK293 cells:> 500 μg/mL, NIH3T3 cells:139.6 μM
In vitro	METHODS: : HEK293 and NIH3T3 were treated with Bekanamycin for 24 hours, and the cell growth inhibition was detected by MTT assay. RESULTS: Bekanamycin did not inhibit the growth of HEK293, with an IC50> 500 μg/mL. Bekanamycin inhibited the growth of NIH3T3, with an IC50=139.6 μM. [1] [2]
Synonyms	Kanamycin B

Chemical Properties

Molecular Weight	483.51
Formula	C₁₈H₃₇N₅O₁₀
Cas No.	4696-76-8
Smiles	O([C@H]1[C@H](O)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](N)[C@H]2O)[C@H](N)C[C@@H]1N)[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3N
Relative Density.	1.59g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 1 mg/mL (2.07 mM), Sonication and heating to 80℃ are recommended.

H2O: 257 mg/mL (531.53 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	2.0682 mL	10.3410 mL	20.6821 mL	103.4105 mL

H2O

	1mg	5mg	10mg	50mg
5 mM	0.4136 mL	2.0682 mL	4.1364 mL	20.6821 mL
10 mM	0.2068 mL	1.0341 mL	2.0682 mL	10.3410 mL
20 mM	0.1034 mL	0.5171 mL	1.0341 mL	5.1705 mL
50 mM	0.0414 mL	0.2068 mL	0.4136 mL	2.0682 mL
100 mM	0.0207 mL	0.1034 mL	0.2068 mL	1.0341 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc