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Brassinazole

Name: Brassinazole
Brand: TargetMol
SKU: T60929
Price: 99 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60929Cas No. 280129-83-1

Alias (2S,3R)-Brassinazole

Brassinazole is a selective inhibitor of triazole-type steroid (BR) biosynthesis.Brassinazole can be used to modulate the oleuropein steroid (BR) signaling pathway, which is used to regulate plant xylem growth and development.

Brassinazole

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Purity: 99.71%

Catalog No. T60929Alias (2S,3R)-BrassinazoleCas No. 280129-83-1

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$99	-	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.71%

Appearance:Solid

Color:White

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Product Introduction

Bioactivity

Description	Brassinazole is a selective inhibitor of triazole-type steroid (BR) biosynthesis.Brassinazole can be used to modulate the oleuropein steroid (BR) signaling pathway, which is used to regulate plant xylem growth and development.
In vitro	At concentrations of 0.5, 1, and 5 μM, Brassinazole induces marked malformation of seedlings, rendering them morphologically similar to BR-deficient mutants. Cress treated with Brassinazole exhibits dwarfism and altered leaf morphology, characterized by downward curling and a dark green color typical of Arabidopsis BR-deficient mutants. This dwarfism is reversed by the application of 10 nM brassinolide [1].
Synonyms	(2S,3R)-Brassinazole

Chemical Properties

Molecular Weight	327.81
Formula	C₁₈H₁₈ClN₃O
Cas No.	280129-83-1
Smiles	[C@H]([C@@](C)(O)C1=CC=CC=C1)(CC2=CC=C(Cl)C=C2)N3C=NC=N3

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (91.52 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0505 mL	15.2527 mL	30.5055 mL	152.5274 mL
5 mM	0.6101 mL	3.0505 mL	6.1011 mL	30.5055 mL
10 mM	0.3051 mL	1.5253 mL	3.0505 mL	15.2527 mL
20 mM	0.1525 mL	0.7626 mL	1.5253 mL	7.6264 mL
50 mM	0.0610 mL	0.3051 mL	0.6101 mL	3.0505 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc