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Dichlormid

Name: Dichlormid
Brand: TargetMol
SKU: T40477
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T40477Cas No. 37764-25-3

Dichlormid, a herbicide safener, up-regulates the expression of ZmMRP1 and ZmGST27 and increases ZmGT1.

Dichlormid

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Purity: 99.80%

Catalog No. T40477Cas No. 37764-25-3

Dichlormid, a herbicide safener, up-regulates the expression of ZmMRP1 and ZmGST27 and increases ZmGT1.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 g	$41	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.80%

Resource Download

COA LCMS HNMR GC

Product Introduction

Dichlormid AI Summary

Dichlormid shows bioactivity in Zea mays (maize) by increasing the glutathione (GSH) content in both roots and shoots when applied at a 50 µM concentration to seeds. It exhibits safening activity against acetochlor-induced phytotoxicity by promoting shoot length increase when applied pre-emergence. The compound demonstrates binding affinity to the SafBP receptor in maize seedlings with an IC50 value of 10.0 nM, as determined by the [3H]Saf(R-29148) binding assay, suggesting a significant interaction with the SafBP receptor. Consequently, Dichlormid has a notable impact on GSH levels and plant growth parameters under these experimental conditions..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Dichlormid, a herbicide safener, up-regulates the expression of ZmMRP1 and ZmGST27 and increases ZmGT1.

Chemical Properties

Molecular Weight	208.09
Formula	C₈H₁₁Cl₂NO
Cas No.	37764-25-3
Smiles	ClC(Cl)C(=O)N(CC=C)CC=C

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (240.28 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (9.61 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.8056 mL	24.0281 mL	48.0561 mL	240.2806 mL
5 mM	0.9611 mL	4.8056 mL	9.6112 mL	48.0561 mL
10 mM	0.4806 mL	2.4028 mL	4.8056 mL	24.0281 mL
20 mM	0.2403 mL	1.2014 mL	2.4028 mL	12.0140 mL
50 mM	0.0961 mL	0.4806 mL	0.9611 mL	4.8056 mL
100 mM	0.0481 mL	0.2403 mL	0.4806 mL	2.4028 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc