Shopping Cart
Remove All
Your shopping cart is currently empty
Selvigaltin
Copy Product Info
🥰Excellent
Catalog No. T63751Cas No. 1978336-95-6
Alias GB1211
Selvigaltin (GB1211) is a Gal-3 inhibitor with potential anticancer activity. Selvigaltin is used in the study of cirrhosis and cancer.
Selvigaltin
Copy Product Info🥰Excellent
Purity: 99.49%
Catalog No. T63751Alias GB1211Cas No. 1978336-95-6
Selvigaltin (GB1211) is a Gal-3 inhibitor with potential anticancer activity. Selvigaltin is used in the study of cirrhosis and cancer.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $278 | In Stock | In Stock | |
| 5 mg | $689 | In Stock | In Stock | |
| 10 mg | $1,180 | In Stock | In Stock | |
| 25 mg | $2,380 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $826 | In Stock | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:99.49%
ee:100%
Appearance:Solid
Color:White
Contact us for more batch information
Product Introduction
Selvigaltin AI Summary
Selvigaltin exhibits a diverse range of bioactivities, demonstrating significant pharmacokinetic and pharmacodynamic properties. The compound has a LogD of 3.0 according to shake-flask analysis, indicating moderate lipophilicity. It inhibits various CYP enzymes, including 2C19, 3A4, 1A2, 2C9, 2D6, 2C8, and 2B6, with inhibition constants greater than 10.0 μM, suggesting low potential for CYP-mediated drug-drug interactions at typical therapeutic concentrations.
Additionally, Selvigaltin shows selective binding affinity to different Galectin proteins, indicating possible targeting specificity and potential therapeutic applications. Its permeability across human Caco-2 cells varies between apical to basolateral and basolateral to apical directions, highlighting its absorption characteristics.
The compound exhibits variable stability in human and mouse hepatocytes with different clearance rates, and its clearance and oral bioavailability have been confirmed in C57BL/6 mice, providing essential pharmacokinetic insights. Moreover, it demonstrates plasma protein binding in both human and mouse plasma, affecting its distribution and free drug concentration.
Selvigaltin inhibits the hERG channel at concentrations below 10.0 μM, indicating a need for cardiac safety assessment. It also displays binding affinity to the rat calcium L channel and the human dopamine transporter, with specific activity percentages, suggesting potential impacts on calcium signaling and neurotransmitter regulation..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Selvigaltin (GB1211) is a Gal-3 inhibitor with potential anticancer activity. Selvigaltin is used in the study of cirrhosis and cancer. |
| Synonyms | GB1211 |
| Molecular Weight | 533.32 |
| Formula | C19H16BrF3N4O4S |
| Cas No. | 1978336-95-6 |
| Smiles | [H][C@@]1([C@@H](O)[C@@H](CO)O[C@H](Sc2cncc(Br)c2)[C@@H]1O)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |
| Storage | keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 265 mg/mL (496.89 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+90% Corn Oil: 1 mg/mL (1.88 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Selvigaltin | purchase Selvigaltin | Selvigaltin cost | order Selvigaltin | Selvigaltin chemical structure | Selvigaltin formula | Selvigaltin molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.