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magnolin

Name: magnolin
Brand: TargetMol
SKU: T3857
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T3857Cas No. 31008-18-1

Alias (+)-Magnolin

Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects.

magnolin

🥰Excellent

Purity: 99.77%

Catalog No. T3857Alias (+)-MagnolinCas No. 31008-18-1

Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects.

Pack Size	Price	Availability
5 mg	$33	In Stock
10 mg	$59	In Stock
25 mg	$105	In Stock
50 mg	$152	In Stock
100 mg	$223	In Stock
200 mg	$329	In Stock
1 mL x 10 mM (in DMSO)	$36	In Stock

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Batch Information

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Purity:99.77%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects.
Targets&IC50	ERK1:87 nM, ERK2:16.5 nM
Synonyms	(+)-Magnolin

Chemical Properties

Molecular Weight	416.46
Formula	C₂₃H₂₈O₇
Cas No.	31008-18-1
Smiles	COc1ccc(cc1OC)[C@H]1OC[C@H]2[C@@H]1CO[C@@H]2c1cc(OC)c(OC)c(OC)c1
Relative Density.	1.178 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (108.05 mM), Sonication is recommended.

H2O: ＜1 mg/mL (insoluble)

Chloroform, Dichloromethane, Ethyl Acetate: Soluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4012 mL	12.0060 mL	24.0119 mL	120.0595 mL
5 mM	0.4802 mL	2.4012 mL	4.8024 mL	24.0119 mL
10 mM	0.2401 mL	1.2006 mL	2.4012 mL	12.0060 mL
20 mM	0.1201 mL	0.6003 mL	1.2006 mL	6.0030 mL
50 mM	0.0480 mL	0.2401 mL	0.4802 mL	2.4012 mL
100 mM	0.0240 mL	0.1201 mL	0.2401 mL	1.2006 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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