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Mesendogen

🥰Excellent
Catalog No. T28020Cas No. 864716-85-8

Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7 magnesium channel activity.

Mesendogen

Mesendogen

🥰Excellent
Purity: 99.66%
Catalog No. T28020Cas No. 864716-85-8
Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7 magnesium channel activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$36In StockIn Stock
5 mg$84In StockIn Stock
10 mg$147In StockIn Stock
25 mg$322In StockIn Stock
50 mg$563In StockIn Stock
100 mg$793In StockIn Stock
1 mL x 10 mM (in DMSO)$95In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.66%
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Product Introduction

Bioactivity
Description
Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7 magnesium channel activity.
Chemical Properties
Molecular Weight400.85
FormulaC18H16ClF3N2OS
Cas No.864716-85-8
SmilesCC(C)c1ccc(cc1)C(=O)NC(=S)Nc1cc(ccc1Cl)C(F)(F)F
Relative Density.1.362 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (137.21 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4947 mL12.4735 mL24.9470 mL124.7349 mL
5 mM0.4989 mL2.4947 mL4.9894 mL24.9470 mL
10 mM0.2495 mL1.2473 mL2.4947 mL12.4735 mL
20 mM0.1247 mL0.6237 mL1.2473 mL6.2367 mL
50 mM0.0499 mL0.2495 mL0.4989 mL2.4947 mL
100 mM0.0249 mL0.1247 mL0.2495 mL1.2473 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TRPVChannelTRPV ChannelTRPM7TRPM6TRPChannelTRP ChannelMesendogen
Related Tags: buy Mesendogen | purchase Mesendogen | Mesendogen cost | order Mesendogen | Mesendogen chemical structure | Mesendogen formula | Mesendogen molecular weight
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