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Raxatrigine hydrochloride

Name: Raxatrigine hydrochloride
Brand: TargetMol
SKU: T14992
Rating: 4.5 (1 reviews)

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Catalog No. T14992Cas No. 934240-31-0

Alias GSK-1014802 hydrochloride, CNV1014802 (hydrochloride)

Raxatrigine hydrochloride is a state-dependent sodium channel blocker and a Nav1.7 sodium channel inhibitor.

Raxatrigine hydrochloride

😃Good

Catalog No. T14992Alias GSK-1014802 hydrochloride, CNV1014802 (hydrochloride)Cas No. 934240-31-0

Raxatrigine hydrochloride is a state-dependent sodium channel blocker and a Nav1.7 sodium channel inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$88	5 days	5 days
5 mg	$178	5 days	5 days
25 mg	$652	1-2 weeks	1-2 weeks
50 mg	$847	1-2 weeks	1-2 weeks
100 mg	$1,340	1-2 weeks	1-2 weeks
1 mL x 10 mM (in DMSO)	$176	5 days	5 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Raxatrigine hydrochloride is a state-dependent sodium channel blocker and a Nav1.7 sodium channel inhibitor.
Synonyms	GSK-1014802 hydrochloride, CNV1014802 (hydrochloride)

Chemical Properties

Molecular Weight	350.82
Formula	C₁₈H₂₀ClFN₂O₂
Cas No.	934240-31-0
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 31 mg/mL (88.36 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8505 mL	14.2523 mL	28.5046 mL	142.5232 mL
5 mM	0.5701 mL	2.8505 mL	5.7009 mL	28.5046 mL
10 mM	0.2850 mL	1.4252 mL	2.8505 mL	14.2523 mL
20 mM	0.1425 mL	0.7126 mL	1.4252 mL	7.1262 mL
50 mM	0.0570 mL	0.2850 mL	0.5701 mL	2.8505 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc