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BRD4-BD1-IN-2

Catalog No. T64117 CAS 2761321-26-8

BRD4-BD1-IN-2 is a selective and potent BRD4-BD1 inhibitor with an IC50 value of 2.51 µM, which is 20-fold greater than the inhibitory activity against BRD4-BD2.BRD4-BD1-IN-2 can be used in the study of cardiovascular and cancer-related diseases.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

BRD4-BD1-IN-2, CAS 2761321-26-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 397.00
5 mg	In stock	$ 970.00
10 mg	In stock	$ 1,180.00
25 mg	In stock	$ 1,580.00
50 mg	In stock	$ 1,980.00
100 mg	In stock	$ 2,500.00

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Purity: 99.47%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	BRD4-BD1-IN-2 is a selective and potent BRD4-BD1 inhibitor with an IC50 value of 2.51 µM, which is 20-fold greater than the inhibitory activity against BRD4-BD2.BRD4-BD1-IN-2 can be used in the study of cardiovascular and cancer-related diseases.
Targets&IC50	BRD4 BD2:50 μM, BRD4 BD1:2.51 μM

Molecular Weight	583.07
Formula	C20H15Br3N4O2
CAS No.	2761321-26-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Chang Y, et al. Design, synthesis, biological evaluation, and molecular docking of 1, 7-dibenzyl-substituted theophylline derivatives as novel BRD4-BD1-selective inhibitors. Medicinal Chemistry Research, 2021, 30(8): 1453-1468.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library

Related Products

Related compounds with same targets

BRD4 Inhibitor-10 PBRM1-BD2-IN-5 PLX51107 GSK1324726A dBET1 NSC 228155 BRM/BRG1 ATP Inhibitor-2 EML 425

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

BRD4-BD1-IN-2 2761321-26-8 Chromatin/Epigenetic Epigenetic Reader Domain inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.