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CTTHWGFTLC, CYCLIC

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Catalog No. TP1501Cas No. 244082-19-7

This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of these enzymes can prevent tumor progression.

CTTHWGFTLC, CYCLIC
Other Forms of CTTHWGFTLC, CYCLIC:
CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)TP1501L
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CTTHWGFTLC, CYCLIC

😃Good
Catalog No. TP1501Cas No. 244082-19-7
This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of these enzymes can prevent tumor progression.
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500 mgInquiryInquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of these enzymes can prevent tumor progression.
Chemical Properties
Molecular Weight1166.33
FormulaC52H71N13O14S2
Cas No.244082-19-7
SmilesC(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CC4=CN=CN4)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@@H](N)CSSC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)CNC3=O)[H])[H])[H]
Relative Density.no data available
SequenceCys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys (Disulfide Bridge: Cys1-Cys10)
Sequence ShortCTTHWGFTLC (Disulfide Bridge: Cys1-Cys10)
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: Soluble

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

CTTHWGFTLC, CYCLIC
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